The 2010 Oregon Ducks football team represented the University of Oregon in the 2010 NCAA Division I FBS football season. The team was led by Chip Kelly in his second season as a head coach. The Ducks played their home games at Autzen Stadium for the 44th straight year.

The 2010 NCAA Division I FBS football season was the highest level of college football competition in the United States organized by the National Collegiate Athletic Association (NCAA).