The 2010 United States Senate election in Utah took place on November 2, 2010, along with other midterm elections throughout the United States. Incumbent Republican U.S. Senator Bob Bennett was seeking re-election to a fourth term, but lost renomination at the Republican Party's state convention. Mike Lee proceeded to win the Republican primary against Tim Bridgewater and the general election against Democrat Sam Granato. As of 2024, this is the most recent U.S. Senate election in which a political party held the seat after denying renomination to the incumbent senator.

Robert Foster Bennett was an American politician and businessman who served as a United States Senator from Utah from 1993 to 2011. A member of the Republican Party, Bennett held chairmanships and senior positions on various key Senate committees, including the Banking, Housing and Urban Affairs Committee; Appropriations Committee; Rules and Administration Committee; Energy and Natural Resources Committee; and Joint Economic Committee.