The 2010 V8 Supercar Championship Series was an FIA sanctioned international motor racing series for V8 Supercars. It was the twelfth V8 Supercar Championship Series and the fourteenth series in which V8 Supercars have contested the premier Australian touring car title. The championship began on 19 February in the Middle East at Abu Dhabi's Yas Marina Circuit and concluded on 5 December at the Homebush Street Circuit. These events were held in all states of Australia and in the Northern Territory as well as in the United Arab Emirates, Bahrain and New Zealand. The 51st Australian Touring Car Championship title was awarded to the winner of the Drivers Championship by the Confederation of Australian Motor Sport.

Triple Eight Race Engineering, branded as Red Bull Ampol Racing in Supercars, is an Australian motor racing team competing in the Supercars Championship. The team has been the only Brisbane-based V8 Supercar team since its formation, originally taking over and operating out of the former Briggs Motor Sport workshop in Bowen Hills during the 2003 season before moving to Banyo in 2009. The team has won the Supercars drivers' championship ten times, the teams' championship eleven times and the Bathurst 1000 ten times.