The 2010 Wyoming gubernatorial election was held on Tuesday, November 2, 2010 to elect the Governor of Wyoming. Party primaries were held on August 17.

Matthew Hansen Mead is a Wyoming attorney, businessman, and politician who served as the 32nd governor of Wyoming from 2011 to 2019. A member of the Republican Party, he previously was the United States Attorney for the District of Wyoming from 2001 to 2007.