The 2012 NCAA Division I women's basketball tournament began March 17 and concluded April 3, 2012. The Final Four was played at Pepsi Center in Denver. For only the second time in history, and the first time since 1989, all four of the number one seeds made it to the Final Four. Baylor won its second national championship, defeating Notre Dame 80–61 in the championship game. They were the only team to win 40 straight games in a season until Connecticut matched it in 2014.

Tara Ann VanDerveer is a retired American basketball coach who was the head women's basketball coach at Stanford University from 1985 until her retirement in 2024. Designated the Setsuko Ishiyama Director of Women's Basketball, VanDerveer led the Stanford Cardinal to three NCAA Women's Division I Basketball Championships: in 1990, 1992 and 2021. She stepped away from the Stanford program for a year to serve as the U.S. national team head coach at the 1996 Olympic Games. VanDerveer is the 1990 Naismith National Coach of the Year and a ten-time Pac-12 Coach of the Year. She is also one of only nine NCAA Women's Basketball coaches to win over 900 games, and one of ten NCAA Division I coaches – women's or men’s – to win 1,000 games. VanDerveer was inducted into the Women's Basketball Hall of Fame in 2002. On December 15, 2020, she passed Pat Summitt for most wins in women's college basketball history. On January 21, 2024, she won her 1,203rd game as a head coach, becoming the head coach with the most wins in college basketball history, women’s or men’s.