The 2014 Major League Baseball season began on March 22 at the Sydney Cricket Ground in Sydney, Australia, between the Los Angeles Dodgers and the Arizona Diamondbacks. The North American part of the season started on March 30 and ended on September 28.

The 2015 Major League Baseball season began on April 5 with a Sunday night game between the St. Louis Cardinals and the Chicago Cubs at Wrigley Field, and ended on November 1 with the Kansas City Royals winning the World Series. This was Rob Manfred's first season serving as Commissioner of Baseball.