The 2015–16 Big East Conference men's basketball season began with practices in October 2015, followed by the start of the followed by the start of the 2015–16 NCAA Division I men's basketball season in November. The season marked the 37th year in the conference's history, but the third as a non-football conference, which officially formed on July 1, 2013. Conference play began on December 30, 2015, and concluded in March with the 2016 Big East men's basketball tournament at Madison Square Garden in New York.

The 2015–16 Villanova Wildcats men's basketball team represented Villanova University in the 2015–16 NCAA Division I men's basketball season. Led by the school's 8th head coach Jay Wright in his 15th year, the Wildcats were members of the Big East Conference and played most of their home games at The Pavilion, with some select home games at the Wells Fargo Center. The Wildcats finished the season with a record of 35–5, 16–2 to win the Big East regular season. They lost in the championship of the Big East tournament to Seton Hall. The Wildcats earned an at-large bid to the NCAA tournament as a No. 2 seed. In the Tournament, they defeated UNC Asheville, Iowa, Miami, and overall #1 seed Kansas to earn a trip to the Final Four, the fifth in school history. In the Final Four, the Wildcats routed No. 2 seed Oklahoma by the largest margin in Final Four history to face No. 1 seeded North Carolina for the national championship. Led by Final Four MOP, Ryan Arcidiacono, the Wildcats won the National Championship on a three-point shot by Kris Jenkins, assisted by Arcidiacano, as time expired. The Wildcats won the school's second national title, having previously won the 1985 NCAA tournament.