The 2015–16 UConn Huskies women's basketball team represented the University of Connecticut in the 2015–16 NCAA Division I women's basketball season. The Huskies, led by thirty first year head coach Geno Auriemma, won the NCAA tournament and went undefeated. With their eleventh championship win in 2016, the UConn Huskies became the first NCAA Division I women's basketball team to win four straight national championships.

Luigi "Geno" Auriemma is an Italian-born American college basketball coach and, since 1985, the head coach of the University of Connecticut Huskies women's basketball team. As of 2021, he has led UConn to 17 undefeated conference seasons, of which six were undefeated overall seasons, with 11 NCAA Division I national championships, the most in women's college basketball history, and has won eight national Naismith College Coach of the Year awards. Auriemma was the head coach of the United States women's national basketball team from 2009 through 2016, during which time his teams won the 2010 and 2014 World Championships, and gold medals at the 2012 and 2016 Summer Olympics, going undefeated in all four tournaments. Auriemma was inducted into the Naismith Memorial Basketball Hall of Fame and the Women's Basketball Hall of Fame in 2006.