The 2015 Coke Zero 400 powered by Coca-Cola was a NASCAR Sprint Cup Series race that was held between July 5 and 6, 2015 at Daytona International Speedway in Daytona Beach, Florida. Contested over 161 laps – extended from the scheduled 160 laps – on the 2.5 mile (4 km) superspeedway, it was the 17th race of the 2015 NASCAR Sprint Cup Series season. Dale Earnhardt Jr. won the race, his second win of the season. His teammate Jimmie Johnson finished second while Denny Hamlin, Kevin Harvick, and Kurt Busch rounded out the top five.

The 2015 NASCAR Sprint Cup Series was the 67th season of professional stock car racing in the United States and the 44th modern-era Cup season. The season began at Daytona International Speedway with the Sprint Unlimited exhibition race, the Budweiser Duels, and the Daytona 500. The season ended with the Ford EcoBoost 400 at Homestead-Miami Speedway. Kyle Busch won the championship, despite missing the first third of the season due to severe leg injuries suffered in an Xfinity Series race at Daytona. Busch also became the first Toyota driver to win a Cup championship. Despite not running the full season, Brett Moffitt was named Rookie of the Year.