The 2015 Motorcycle Grand Prix of the Americas was the second round of the 2015 Grand Prix motorcycle racing season. It was held at the Circuit of the Americas in Elroy on April 12, 2015.

The 2015 FIM MotoGP World Championship was the premier class of the 67th F.I.M. Road Racing World Championship season. The championship was won by Spanish rider Jorge Lorenzo, racing for Movistar Yamaha MotoGP. It was his third and final world title in the MotoGP category, his fifth overall in Grand Prix motorcycle racing. The season had 18 races, beginning in Qatar and finishing in Valencia, which determined who would be world champion between Movistar Yamaha teammates Lorenzo and runner-up Valentino Rossi. It was first time since 2013 that the world title was decided on the final race of the season. Lorenzo also had the most pole positions, fastest laps and race wins throughout the season; while Rossi had the most finishes, completing every race throughout the season, while Lorenzo had one race retirement in San Marino.