The 2015 Tour of Flanders was the 99th edition of the Tour of Flanders one-day cycling race. It took place on 5 April and was the eighth race of the 2015 UCI World Tour. The race was one of the cobbled classics and was the second of the cycling monuments on the 2015 calendar. The 2014 champion was Fabian Cancellara; he was not able to defend his title after breaking two vertebrae in a crash at E3 Harelbeke.

John Degenkolb is a German professional road bicycle racer, who rides for UCI WorldTeam Team dsm–firmenich PostNL. His biggest wins to date are the 2015 Milan–San Remo and the 2015 Paris–Roubaix, two of cycling's five monuments. He is a winner of stages in all three Grand Tours, with ten stages and the points classification at the Vuelta a España, one stage of the Giro d'Italia, and one stage in the Tour de France.