The 2016–17 Iowa State Cyclones men's basketball team represented Iowa State University during the 2016–17 NCAA Division I men's basketball season. The Cyclones were coached by Steve Prohm, who was in his second season. They played their home games at Hilton Coliseum in Ames, Iowa as members of the Big 12 Conference. They finished the season 24–11, 12–6 in Big 12 play to finish in a three-way tie for second place. In the Big 12 tournament, they defeated Oklahoma State, TCU, and West Virginia to win the tournament championship. As a result, they received the conference's automatic bid to the NCAA tournament. As the No. 5 seed in the Midwest region, they defeated Nevada in the First Round before losing to Purdue in the Second Round.

Steven Marshall Prohm is an American basketball coach who is in his second tenure as the head coach for Murray State men's basketball. Previously, he was the head coach at Iowa State University, a position he had held from 2015 to 2021. Prohm served in the same capacity at Murray State University from 2011 to 2015.