The 2016–17 season was Port Vale's 105th season of football in the English Football League, and fourth-successive season in EFL League One. Vale finished in 21st place – one point from safety – and were relegated. The season covers the period from 1 July 2016 through to 30 June 2017.

Port Vale Football Club are a professional football club based in Burslem, Stoke-on-Trent, England, which compete in EFL League One but will play in EFL League Two in the 2024–25 season after suffering relegation. Vale are named after the valley of ports on the Trent and Mersey Canal. They have never played top-flight football, and hold the record for the most seasons in the English Football League (112) without reaching the first tier. After playing at the Athletic Ground in Cobridge and The Old Recreation Ground in Hanley, the club returned to Burslem when Vale Park was opened in 1950. Outside the ground is a statue to Roy Sproson, who played 842 competitive games for the club. The club's traditional rivals are Stoke City, and games between the two are known as the Potteries derby.