On March 11, 2016, the Donald Trump presidential campaign canceled a planned rally at the University of Illinois Chicago (UIC), in Chicago, Illinois, citing "growing safety concerns" due to the presence of thousands of protesters inside and outside his rally.

The 2016 presidential campaign of Donald Trump was formally launched on June 16, 2015, at Trump Tower in New York City. Trump was the Republican nominee for President of the United States in the 2016 election, having won the most state primaries, caucuses, and delegates at the 2016 Republican National Convention. He chose Mike Pence, the sitting governor of Indiana, as his vice presidential running mate. On November 8, 2016, Trump and Pence were elected president and vice president of the United States. Trump's populist positions in opposition to illegal immigration and various trade agreements, such as the Trans-Pacific Partnership, earned him support especially among voters who were male, white, blue-collar, working class, and those without college degrees. Many voters in the Rust Belt, who gave Trump the electoral votes needed to win the presidency, switched from supporting Bernie Sanders to Trump after Hillary Clinton won the Democratic nomination.