The 2016 Major League Baseball draft began on June 9, 2016, to assign amateur baseball players to MLB teams. The draft order is the reverse order of the 2015 MLB season standings. In addition, compensation picks will be distributed for players who did not sign from the 2015 MLB Draft. The Philadelphia Phillies received the first overall selection. The Los Angeles Dodgers received the 36th pick as compensation for failing to sign Kyle Funkhouser, the 35th overall selection of the 2015 MLB Draft.

Matthew George Manning is an American professional baseball pitcher for the Detroit Tigers of Major League Baseball (MLB). The Tigers selected him in the first round of the 2016 MLB draft and he made his MLB debut in 2021.