The 2016 Monaco Grand Prix was a Formula One motor race held on 29 May 2016 at the Circuit de Monaco, a street circuit that runs through the Principality of Monaco. It was the sixth round of the 2016 FIA Formula One World Championship, and marked the seventy-fourth time that the Monaco Grand Prix had been held, as well as the sixty-third time it had been held as a round of the Formula One World Championship since the series inception in 1950.

Circuit de Monaco is a 3.337 km (2.074 mi) street circuit laid out on the city streets of Monte Carlo and La Condamine around the harbour of the Principality of Monaco. It is commonly, and even officially, referred to as "Monte Carlo" because it is largely inside the Monte Carlo neighbourhood of Monaco.