The 2016 NCAA Division I men's basketball championship game was the final game of the 2016 NCAA Division I men's basketball tournament and determined the national champion for the 2015–16 NCAA Division I men's basketball season. The game was played on Monday, April 4, 2016, at NRG Stadium in Houston, Texas, between the Villanova Wildcats and the North Carolina Tar Heels.

The 2016 NCAA Division I men's basketball tournament involved 68 teams playing in a single-elimination tournament to determine the men's National Collegiate Athletic Association (NCAA) Division I college basketball national champion for the 2015–16 season. The 78th edition of the Tournament began on March 15, 2016, and concluded with the championship game on April 4 at NRG Stadium in Houston, Texas. This was the first NCAA tournament to adopt the NCAA March Madness branding, including fully-branded courts at each of the tournament venues.