The 2016 United States Senate election in Indiana was held on November 8, 2016, to elect a member of the United States Senate to represent the State of Indiana. The election was held alongside the presidential election and 2016 Indiana elections.

Daniel Ray Coats is an American politician, attorney, and diplomat. From 2017 to 2019, he served as the Director of National Intelligence in the Trump administration. A member of the Republican Party, he served as a United States Senator from Indiana from 1989 to 1999 and again from 2011 to 2017. He was the United States Ambassador to Germany from 2001 to 2005, and a member of the United States House of Representatives from 1981 to 1989. Coats served on the United States Senate Select Committee on Intelligence while in the U.S. Senate.