The 2017 O'Reilly Auto Parts 500 was a Monster Energy NASCAR Cup Series race held on April 9, 2017, at Texas Motor Speedway in Fort Worth, Texas. Contested over 334 laps on the 1.5-mile (2.4 km) intermediate quad-oval, it was the seventh race of the 2017 Monster Energy NASCAR Cup Series season.

The 2017 Monster Energy NASCAR Cup Series was the 69th season of professional stock car racing in the United States, and the 46th modern-era Cup series season. The season began at Daytona International Speedway with the Advance Auto Parts Clash, the Can-Am Duel qualifying races and the 59th running of the Daytona 500. The season ended with the Ford EcoBoost 400 at Homestead-Miami Speedway. Jimmie Johnson entered the season as the defending champion, having won his record-tying seventh Cup championship that he shares with Richard Petty and Dale Earnhardt. Martin Truex Jr. of Furniture Row Racing won the championship, his first in the series. Toyota won the Manufacturers' Championship for the second year in a row.