The 2018 Breeders' Cup Classic was the 35th running of the Breeders' Cup Classic, part of the 2018 Breeders' Cup World Thoroughbred Championships program. It was run on November 3, 2018, at Churchill Downs in Louisville, Kentucky with a purse of $6,000,000. It was won by Accelerate, who earned his fifth Grade I win of the year.

The Breeders' Cup Classic is a Grade I Weight for Age thoroughbred horse race for 3-year-olds and older run at a distance of 1+1⁄4 miles (2,000 m) on dirt. It is held annually at a different racetrack in the United States as part of the Breeders' Cup World Championships in late October or early November. All of the races to date have been held in the United States except for the 1996 edition held at Woodbine Racetrack in Toronto, Canada.