The 2018 Daytona 500, the 60th running of the event, was a Monster Energy NASCAR Cup Series race held on February 18, 2018, contested over 207 laps—extended from 200 laps due to an overtime finish—on the 2.5-mile (4.0 km) asphalt superspeedway. It was the first race of the 2018 Monster Energy NASCAR Cup Series season, and also marked the first race for the Chevrolet Camaro ZL1 as Chevrolet's car for this season, replacing the SS. Austin Dillon of Richard Childress Racing won the race after contact with Aric Almirola on the final lap resulted in a single-car accident for the latter. Bubba Wallace making his first Daytona 500 start finished second while Denny Hamlin came in third. This was the last Daytona 500 starts for Danica Patrick, Trevor Bayne, Kasey Kahne, David Gilliland, Mark Thompson, BK Racing, Furniture Row Racing and D. J. Kennington.

The Daytona 500 is a 500-mile-long (805 km) NASCAR Cup Series motor race held annually at Daytona International Speedway in Daytona Beach, Florida. It is the first of two Cup races held every year at Daytona, the second being the Coke Zero Sugar 400, and one of three held in Florida, with the annual fall showdown Dixie Vodka 400 being held at Homestead south of Miami. From 1988 to 2019, it was one of the four restrictor plate races on the Cup schedule. The inaugural Daytona 500 was held in 1959 coinciding with the opening of the speedway and since 1982, it has been the season-opening race of the Cup series.