The 2018 Florida Commissioner of Agriculture election occurred on November 6, 2018, to elect the Florida Commissioner of Agriculture. Incumbent Republican Commissioner of Agriculture Adam Putnam was term-limited and could not seek a third consecutive term. Democrat Nikki Fried narrowly defeated Republican Matt Caldwell. Fried became the only statewide elected Democrat in Florida, as U.S. Senator Bill Nelson, who had held Florida's Class I U.S. Senate seat since 2000, lost reelection. As of 2023, this remains the last time that a Democrat has won a statewide election in Florida, and the only time since 2012.

Nicole Heather Fried is an American lawyer and politician who has served as the chair of the Florida Democratic Party since 2023. Prior to her election as chair, Fried served as the 12th Florida commissioner of agriculture from 2019 to 2023. A member of the Democratic Party, Fried graduated from the University of Florida in 2003. She has previously practiced various forms of law, including corporate law, foreclosure defense, and public defense. Fried has also been a prominent lobbyist for the marijuana industry in the state of Florida.