The 2018 United States Senate election in Pennsylvania took place on November 6, 2018, to elect a member of the United States Senate to represent the State of Pennsylvania, concurrently with other elections to the United States Senate, elections to the United States House of Representatives, and various state and local elections. The primary elections were held on May 15. Incumbent Democratic Senator Bob Casey Jr. ran for re-election to a third term. Casey, who faced no primary opposition, defeated the Republican nominee, Lou Barletta, Green Party nominee Neal Gale, and Libertarian Party nominee Dale Kerns. Casey was the first senator to be elected to a third term from Pennsylvania since Arlen Specter in 1992, and the first Pennsylvania Democrat to be popularly elected to three terms in the Senate.

The 2018 United States House of Representatives elections were held on November 6, 2018, as part of the 2018 midterm elections during President Donald Trump's term, with early voting taking place in some states in the weeks preceding that date. Voters chose representatives from all 435 congressional districts across each of the 50 U.S. states to serve in the 116th United States Congress. Non-voting delegates from the District of Columbia and four of the five inhabited U.S. territories were also elected. On Election Day, Republicans had held a House majority since January 2011.