Manila held its local elections on Monday, May 13, 2019, as a part of the 2019 Philippine general election. Voters elected candidates for mayor, vice mayor, 6 congressmen, and the 36 councilors that would be members of the City Council. There are a total of 736,156 people who voted out of the 1,065,149 city's registered voters. Francisco "Isko Moreno" Domagoso won the elections, enabling him to serve a three-year term as the mayor of Manila. His running mate, the incumbent vice mayor Maria Sheilah "Honey" Lacuna-Pangan, once again topped the vice mayoral race, securing her to serve her second three-year term as the city's vice mayor.

The city mayor of Manila is the head of the executive branch of Manila's city government. The mayor holds office at Manila City Hall. Like all local government heads in the Philippines, the mayor is elected via popular vote, and may not be elected for a fourth consecutive term. In case of death, resignation or incapacity, the vice mayor becomes the mayor.