The 2019 NCAA Division I baseball tournament was a tournament of 64-teams to determine the National Collegiate Athletic Association (NCAA) Division I national champion for the 2019 season. The 73rd annual edition of the tournament began on May 31, 2019, and concluded with the 2019 College World Series in Omaha, Nebraska, which started on June 15 and ended on June 26.

The East Carolina Pirates baseball team is an intercollegiate baseball team representing East Carolina University in NCAA Division I college baseball and participates as a full member of the American Athletic Conference. The Pirates have made regular appearances in the NCAA tournament. As of 2023, they have the most NCAA tournament appearances without a College World Series appearance.