The 2019 SMU Mustangs football team represented Southern Methodist University during the 2019 NCAA Division I FBS football season. The Mustangs were led by second-year head coach Sonny Dykes and played their home games at Gerald J. Ford Stadium in University Park, Texas, a separate city within the city limits of Dallas. They competed as members of the West Division of the American Athletic Conference.

Daniel "Sonny" Dykes is an American football coach, and a former college baseball player. He is currently the head football coach at Texas Christian University (TCU), and previously served in the same role at Southern Methodist University (SMU) from 2018 to 2021, the University of California, Berkeley from 2013 to 2016, and Louisiana Tech University from 2010 to 2012. In his first season at TCU, he led the Horned Frogs to a win in the semifinal and an appearance in the National Championship game.