Defending champion Novak Djokovic defeated Roger Federer in the final, 7–6(7–5), 1–6, 7–6(7–4), 4–6, 13–12(7–3) to win the gentlemen's singles tennis title at the 2019 Wimbledon Championships. At four hours and 57 minutes in length, it was the longest singles final in Wimbledon history. It was Djokovic's fifth Wimbledon title and 16th major title overall. Djokovic became the first man since Bob Falkenburg in 1948 to win the title after being championship points down, having saved two when down 7–8 in the fifth set. This was the first time since the 2004 French Open that a man saved championship points in order to win a major. Djokovic became the second man and third singles player overall to win multiple major titles after saving match point during the tournament, after Rod Laver and Serena Williams. Conversely, this was the third time that an opponent of Federer saved match points and went on to win the major, following Marat Safin in the 2005 Australian Open and Djokovic in the 2011 US Open.

The tennis rivalry between Roger Federer and Rafael Nadal is considered one of the greatest in the history of the sport. Federer and Nadal played each other 40 times, with Nadal leading 24–16 overall, including 14–10 in finals.