The 2020 Alsco Uniforms 500 was a NASCAR Cup Series race scheduled to be held on May 27, 2020, but run on May 28, 2020 due to Tropical Depression Bertha at Charlotte Motor Speedway in Concord, North Carolina, replacing Sonoma Raceway event. Contested over 208 laps on the 1.5 mile (2.42 km) asphalt speedway, it was the eighth race of the 2020 NASCAR Cup Series season.

The 2020 NASCAR Cup Series was the 72nd season for NASCAR professional stock car racing in the United States and the 49th season for the modern era Cup Series. The season began at Daytona International Speedway with the Busch Clash, the Bluegreen Vacations Duel qualifying races, and the 62nd running of the Daytona 500. The regular season ended with the Coke Zero Sugar 400 at Daytona on August 29. The NASCAR playoffs ended with the Season Finale 500, the first finale at Phoenix Raceway on November 8.