The 2020 Missouri gubernatorial election was held on November 3, 2020, to elect the Governor of Missouri, concurrently with the 2020 U.S. presidential election, as well as elections to the United States Senate, elections to the United States House of Representatives, and various state and local elections. Incumbent Republican Governor Mike Parson ran for and was elected to a full term in office. Parson was elected as lieutenant governor in 2016 but became governor on June 1, 2018, after incumbent Eric Greitens resigned under threat of impeachment by the state legislature. Parson declared his bid for a full term on September 8, 2019. State Auditor Nicole Galloway, Missouri's only Democratic statewide officer and only female statewide officer, was the Democratic nominee and if elected, would have become Missouri's first female governor.

The 2020 United States presidential election in Missouri was held on Tuesday, November 3, 2020, as part of the 2020 United States presidential election in which all 50 states plus the District of Columbia participated. Missouri voters chose electors to represent them in the Electoral College via a popular vote, pitting the Republican Party's nominee, incumbent President Donald Trump of Florida, and running mate Vice President Mike Pence of Indiana against Democratic Party nominee, former Vice President Joe Biden of Delaware, and his running mate Senator Kamala Harris of California. Missouri has 10 electoral votes in the Electoral College.