The 2020 United States Senate election in Oregon was held on November 3, 2020, to elect a member of the United States Senate to represent the State of Oregon, concurrently with the 2020 U.S. presidential election, as well as other elections to the United States Senate, elections to the United States House of Representatives and various state and local elections. Incumbent Democratic senator Jeff Merkley won reelection to a third term in office. Although this Senate seat was largely expected to be one of the safest for the Democrats, the race received national attention due to the Republican nominee Jo Rae Perkins's promotion of the unfounded QAnon conspiracy theory. Furthermore, Perkins had flipped five counties that Merkley had won in 2014.

Jeffrey Alan Merkley is an American politician serving as the junior United States senator from Oregon since 2009. A member of the Democratic Party, he served from 1999 to 2009 as the representative for the 47th district in the Oregon House of Representatives, which covers central Multnomah County on the eastern side of Portland; he was the speaker of the House during the last two years of his tenure.