The 2021 EuroLeague Final Four was the concluding EuroLeague Final Four tournament of the 2020–21 EuroLeague season, the 64th season of Europe's premier club basketball tournament, and the 21st season since it was first organised by Euroleague Basketball. It was the 34th Final Four of the modern EuroLeague Final Four era (1988–present), and the 36th time overall that the competition has concluded with a final four format. The Final Four was played at the Lanxess Arena in Cologne, Germany, on 28–30 May 2021. The Final Four was played behind closed doors as a consequence of the COVID-19 pandemic and the corresponding measures taken by German authorities.

The 2020–21 Turkish Airlines EuroLeague was the 21st season of the modern era of the EuroLeague and the 11th under the title sponsorship of Turkish Airlines. Including the competition's previous incarnation as the FIBA Europe Champions Cup, this was the 64th season of the premier basketball competition for European men's clubs. The season started 1 October 2020.