A mayoral election was held on November 2, 2021, to elect the mayor of the U.S. city of Minneapolis. Incumbent DFL mayor Jacob Frey won reelection to a second term, becoming the first Minneapolis mayor to win a second term since R. T. Rybak in 2005. Minneapolis mayoral elections use instant-runoff voting, also known as ranked-choice voting. All candidates appear on the same ballot and there is no primary election, nor is there a runoff. Minneapolis's twin city, Saint Paul, also held a mayoral election on the same day, using the same system.

Jacob Lawrence Frey is an American politician and attorney who has served as the mayor of Minneapolis, Minnesota since 2018. A member of the Minnesota Democratic–Farmer–Labor Party, he served on the Minneapolis City Council from 2014 to 2018.