The 2021 NCAA Division I men's basketball championship game was the final game of the 2021 NCAA Division I men's basketball tournament.

The 2021 NCAA Division I men's basketball tournament was a single-elimination tournament of 68 teams to determine the National Collegiate Athletic Association (NCAA) Division I men's college basketball national champion for the 2020–21 season. The 82nd edition of the tournament began play on March 18, 2021 in sites around the state of Indiana, and concluded with the championship game at Lucas Oil Stadium in Indianapolis on April 5, with the Baylor Bears defeating the previously undefeated Gonzaga Bulldogs 86–70 to earn the team's first ever title.