The 2021 Virginia House of Delegates election for the 162nd Virginia General Assembly were held on November 2, 2021 to coincide with biennial elections in the U.S. state of Virginia. All 100 Delegates are elected to two-year terms in single-member constituencies. Primary elections took place on June 8. This election coincided with the 2021 Virginia Gubernatorial election, the Lieutenant Gubernatorial election, and lastly, the Attorney General election, all of which were won by Republicans. The upper house of the Virginia General Assembly, the Senate of Virginia, will hold its next election on November 7, 2023.

The Virginia House of Delegates is one of the two houses of the Virginia General Assembly, the other being the Senate of Virginia. It has 100 members elected for terms of two years; unlike most states, these elections take place during odd-numbered years. The House is presided over by the Speaker of the House, who is elected from among the House membership by the Delegates. The Speaker is usually a member of the majority party and, as Speaker, becomes the most powerful member of the House. The House shares legislative power with the Senate, the upper house of the General Assembly. The House of Delegates is the modern-day successor to the colonial House of Burgesses, which first met at Jamestown in 1619. The House is divided into Democratic and Republican caucuses. In addition to the Speaker, there is a majority leader, majority whip, majority caucus chair, minority leader, minority whip, minority caucus chair, and the chairs of the several committees of the House.