A terrorist attack occurred on İstiklal Avenue in the Beyoğlu district of Istanbul, Turkey, on 13 November 2022, killing 6 people and injuring 81 others.

İstiklal Avenue is a 1.4 kilometre (0.87 mi) pedestrian street in the historic Beyoğlu (Pera) district in Istanbul, Turkey. It is one of the most famous avenues in the city. It acquired its modern name after the declaration of the Republic on 29 October 1923, İstiklal (Independence) commemorating Turkey's triumph in its War of Independence.