The 2022 NRL Grand Final was the conclusive and premiership-deciding game of the 2022 National Rugby League season in Australia. It was contested between the Penrith Panthers and the Parramatta Eels on Sunday the 2nd of October at Accor Stadium in Sydney. Penrith, who were both the defending premiers and minor premiers, won the match 28–12 to claim their fourth premiership title, and their first back-to-back premierships in the club's 56-year history. Panthers fullback Dylan Edwards was awarded the Clive Churchill Medal for being judged as the man of the match.

The Penrith Panthers are an Australian professional rugby league football club based in the Greater Western Sydney suburb of Penrith that competes in the National Rugby League (NRL). The team is based 55 km (34 mi) west of the centre of Sydney, at the foot of the Blue Mountains. Penrith are the current reigning NRL Premiers, having won the title five times, including the last three times consecutively.