The 2022 Princess Auto Players' Championship was held April 12–17 at the Mattamy Athletic Centre in Toronto, Ontario. It was the fourth Grand Slam and final major of the 2021–22 curling season, following the cancellation of the Meridian Open.

The Players' Championship, currently known as the Princess Auto Players' Championship for sponsorship reasons, is the final event of the Grand Slam of Curling tour, and is formerly the championship of the World Curling Tour season.