The 2022 Rachael Heyhoe Flint Trophy was the third edition of the Rachael Heyhoe Flint Trophy, an English women's cricket 50-over domestic competition, which took place between 2 July and 25 September 2022. It featured eight teams playing in a round-robin group, followed by a knock-out round. The holders were the Southern Vipers, who won the first two editions of the competition. It ran alongside the Charlotte Edwards Cup. The tournament was named after former England captain Rachael Heyhoe Flint, Baroness Heyhoe-Flint, who died in 2017.

The Blaze, previously known as Lightning, are a women's cricket team that represent the East Midlands region, one of eight regional hubs in English domestic women's cricket. They play their home matches at various grounds, including Trent Bridge and Grace Road. They are captained by Kirstie Gordon and coached by Chris Guest. The team carries over many elements of the WCSL team Loughborough Lightning. They are partnered with Nottinghamshire, Leicestershire, Derbyshire and Lincolnshire.