The 2022 Lamar Hunt U.S. Open Cup Final was a soccer match played on September 7, 2022, at Exploria Stadium in Orlando, Florida, United States. It was played to determine the winner of the 2022 U.S. Open Cup, the 107th edition of the oldest competition in U.S. soccer, which is open to amateur and professional soccer teams affiliated with the United States Soccer Federation.

Inter&Co Stadium is a soccer-specific stadium in downtown Orlando, Florida. The stadium is located along West Church Street in the Parramore neighborhood west of Downtown Orlando. It is the home of Orlando City SC, which entered Major League Soccer (MLS) as an expansion franchise in 2015, and their National Women's Soccer League (NWSL) affiliate club, the Orlando Pride. The stadium was completed in time for Orlando City's home opener of the 2017 season on March 5 and it became the first ever venue to permanently host MLS, NWSL, and USL teams all in the same location that year. Originally known as Orlando City Stadium, on June 4, 2019, it was announced that Exploria Resorts had acquired naming rights to the stadium. On January 18, 2024, Brazilian digital bank Inter&Co secured the naming rights to the stadium.