The 2022 United States Senate election in Colorado was held on November 8, 2022, to elect a member of the United States Senate to represent the State of Colorado. Incumbent Democratic Senator Michael Bennet won reelection to a third full term, defeating Republican businessman Joe O'Dea. Originally appointed to the seat in 2009, Bennet won full terms in 2010 and 2016.

Michael Farrand Bennet is an American attorney, businessman, and politician serving as the senior United States senator from Colorado, a seat he has held since 2009. A member of the Democratic Party, he was appointed to the seat when Senator Ken Salazar became Secretary of the Interior. Bennet previously worked as a managing director for the Anschutz Investment Company, chief of staff to Denver mayor John Hickenlooper, and superintendent of Denver Public Schools.