The 21 Club, often simply 21, was a traditional American cuisine restaurant and former prohibition-era speakeasy, located at 21 West 52nd Street in New York City. Prior to its closure in 2020, the club had been active for 90 years, and it had hosted almost every US president since Franklin Delano Roosevelt. It had a hidden wine cellar where it stored the collections of celebrities such as Elizabeth Taylor and Sophia Loren.

A speakeasy, also called a blind pig or blind tiger, was an illicit establishment that sold alcoholic beverages. The term may also refer to a retro style bar that replicates aspects of historical speakeasies.