The 26th Tactical Missile Squadron is an inactive United States Air Force unit. It was activated in 1959 as the 26th Air Defense Missile Squadron to provide missile air defense for New England and was stationed at Otis Air Force Base, Massachusetts, where it was inactivated on 30 April 1972. It received its current name in 1985. when it was consolidated with the 26th Tactical Reconnaissance Squadron, a World War II unit that provided reconnaissance support for ground units in training until it was disbanded in 1943.

Otis Air National Guard Base is an Air National Guard installation located within Joint Base Cape Cod, a military training facility located on the western portion of Cape Cod in Barnstable County, Massachusetts, United States. It was known as Otis Air Force Base prior to its transfer from the active duty Air Force to the Air National Guard. In the local community, it is more commonly known as Otis Air Base or simply Otis. It was named in honor of pilot and Boston surgeon Lt. Frank "Jesse" Otis.