The 2nd Minnesota Infantry Regiment was a Minnesota USV infantry regiment that served in the Union Army during the American Civil War. The regiment went on to campaign in the south and especially distinguish itself at the battles of Mill Springs, Chickamauga, and Missionary Ridge.

The Battle of Mill Springs, also known as the Battle of Fishing Creek in the Confederacy, and the Battle of Logan's Cross Roads or Battle of Somerset in the Union, was fought in Wayne and Pulaski counties, near current Nancy, Kentucky, on January 19, 1862, as part of the American Civil War. The Union victory concluded an early Confederate offensive campaign in south central Kentucky.