The 2nd Annual Streamy Awards, presented by the International Academy of Web Television, was the second installment of the Streamy Awards honoring streaming television series. The awards were held on Sunday, April 11, 2010, at the Orpheum Theatre in Los Angeles, California. Paul Scheer served as the host of the presentation. Over 1,300 audience members were in attendance and the show was broadcast live online.

The YouTube Streamy Awards, also known as the Streamy Awards or Streamys, are an awards show presented annually by Dick Clark Productions and Tubefilter to recognize excellence in online video, including directing, acting, producing, and writing. The formal ceremony at which the awards are presented takes place in Los Angeles, California. They were the first ever awards show dedicated entirely to web series.