A 6×4 or six-by-four is a vehicle with three axles, with a drivetrain delivering power to wheels at the ends of two of them. It is a form of four-wheel drive but not one of all-wheel drive.

A drivetrain or Transmission System, is the group of components that deliver mechanical power from the prime mover to the driven components. In automotive engineering, the drivetrain is the components of a motor vehicle that deliver power to the drive wheels. This excludes the engine or motor that generates the power. In marine applications, the drive shaft will drive a propeller, thruster, or waterjet rather than a drive axle, while the actual engine might be similar to an automotive engine. Other machinery, equipment and vehicles may also use a drivetrain to deliver power from the engine(s) to the driven components.