65 Broadway, formerly the American Express Building, is a building on Broadway between Morris and Rector Streets in the Financial District of Manhattan in New York City. The 21-story concrete and steel-frame structure, an office building, was designed by James L. Aspinwall of the firm Renwick, Aspinwall & Tucker in the Neoclassical style. 65 Broadway extends westward through an entire block, to Trinity Place. Its most prominent feature is its H-shaped building plan, with light courts located between its wings.

Church Street and Trinity Place form a single northbound roadway in Lower Manhattan, New York City. Its northern end is at Canal Street and its southern end is at Morris Street, where Trinity Place merges with Greenwich Street. The dividing point is Liberty Street.