The 6th arrondissement of Paris is one of the 20 arrondissements of the capital city of France. In spoken French, it is referred to as le sixième.

The Luxembourg Palace is at 15 Rue de Vaugirard in the 6th arrondissement of Paris, France. It was originally built (1615–1645) to the designs of the French architect Salomon de Brosse to be the royal residence of the regent Marie de' Medici, mother of King Louis XIII. After the Revolution it was refashioned (1799–1805) by Jean Chalgrin into a legislative building and subsequently greatly enlarged and remodeled (1835–1856) by Alphonse de Gisors. The palace has been the seat of the upper houses of the various French national legislatures since the establishment of the Sénat conservateur during the Consulate; as such, it has been home to the Senate of the Fifth Republic since its establishment in 1958.