The 78th Academy Awards presented by the Academy of Motion Picture Arts and Sciences (AMPAS), took place on March 5, 2006, at the Kodak Theatre in Hollywood, Los Angeles beginning at 5:00 p.m. PST / 8:00 p.m. EST. The ceremony was scheduled one week later than usual to avoid a clash with the 2006 Winter Olympics. During the ceremony, AMPAS presented Academy Awards in 24 categories honoring films released in 2005. The ceremony, televised in the United States by ABC, was produced by Gil Cates and directed by Louis J. Horvitz. Actor Jon Stewart hosted the show for the first time. Two weeks earlier in a ceremony at The Beverly Hilton in Beverly Hills, California held on February 18, the Academy Awards for Technical Achievement were presented by host Rachel McAdams.

Jon Stewart is an American comedian, writer, producer, director, political commentator, actor, and television host. The long-running host of The Daily Show on Comedy Central from 1999 to 2015, Stewart returned to the satirical news program in 2024. He hosted The Problem with Jon Stewart on Apple TV+ from 2021 to 2023. Stewart has received numerous accolades, including 22 Primetime Emmy Awards, two Grammy Awards, and five Peabody Awards. He was honored with the Bronze Medallion in 2019, and the Mark Twain Prize for American Humor in 2022.