The 850th Strategic Missile Squadron is an inactive United States Air Force unit. It was last assigned to the 44th Strategic Missile Wing at Ellsworth Air Force Base, South Dakota, where it was inactivated on 25 March 1965. The squadron was first activated in 1943 as the 850th Bombardment Squadron. After training in the United States, it deployed to the European Theater of Operations and participated in the strategic bombing campaign against Germany. Following V-E Day, the squadron returned to the United States, where it was inactivated in November 1945.

The 44th Missile Wing is an inactive United States Air Force unit. Its last assignment was with Twentieth Air Force, being assigned to Ellsworth AFB, South Dakota. It was inactivated on 4 July 1994.