The A726 road in Scotland is a major route with several distinct sections with different characteristics and names; owing to its stages of construction, since 2005 it has two separate parts, the first running between Strathaven in South Lanarkshire and Junction 5 of the M77 motorway south of Newton Mearns in East Renfrewshire via East Kilbride, and the other running between Junction 3 of the M77 and the M898 motorway near the Erskine Bridge, via Paisley and Junction 29 of the M8 motorway near Glasgow International Airport.

Strathaven is a historic market town in South Lanarkshire, Scotland and is the largest settlement in Avondale. It is 7.5 kilometres south of Hamilton. The Powmillon Burn runs through the town centre, and joins the Avon Water to the east of the town.